Autosomal dominant polycystic kidney disease

ADPKD is an autosomal dominant disorder caused by mutations in one of the genes PKD1 or PKD2. It manifests in adults and one half of patient develop end stage renal disease.

Epidemiology

The estimated prevalence is between 1 one in 500 to 1 in 2000.

Systematic

Cystic kidney disease
	Alagille syndrome 2
	Autosomal dominant polycystic kidney disease
		Polycystic kidney disease 1
			PKD1
		Polycystic kidney disease 2
			PKD2
		Polycystic kidney disease 3
			GANAB
		Polycystic kidney disease 6
			DNAJB11
	Autosomal recessive polycystic kidney and hepatic disease 1
	Branchiootorenal dysplasia
	Glomerulocystic kidney disease with hyperuricemia and isosthenuria
	Hajdu-Cheney syndrome
	Medullary cystic disease complex
	Polycystic kidney disease with hyperinsulinemic hypoglycemia
	Renal cysts and diabetes (RCAD)