Clinical feature: 

Definition: Bronchiectasis with or without elevated sweat chloride type 3 is an autosomal recessive disorder caused by mutations of the SCNN1G gene. Mutations not only account for a systic fibrosis-like disease but also typical cystic fibrosis can be aggravated.

Literature: 

Fajac I et al. (2008) Could a defective epithelial sodium channel lead to bronchiectasis.
Mutesa L et al. (2009) Genetic analysis of Rwandan patients with cystic fibrosis-like symptoms: identification of novel cystic fibrosis transmembrane conductance regulator and epithelial sodium channel gene variants.