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Thrombasthenia of Glanzmann and Naegeli

Glanzmann thrombasthenia is a rare autosomal recessive bleeding disorder as a result of platelet's inability to bind fibrinogen and form clots. This failure is caused by glycoprotein IIb-IIIa complex deficiency. Underlying mutations can be found in two distinct genes, ITGA2B and ITGB3.

Systematic

Inheritable platelet disorders
Alloimmune thrombocytopenia
Autoinflammatory periodic fever, immunodeficiency, and thrombocytopenia
Bernard-Soulier syndrome
Bleeding disorder platelet-type 9
Glycoprotein 1a deficiency
IVIC syndrome
MYH9 related disorders
Mediterranean macrothrombocytopenia
Thrombasthenia of Glanzmann and Naegeli
ITGA2B
ITGB3
Thrombocythemia 3
Wiskott–Aldrich syndrome
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