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Juvenile onset glaucoma
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Juvenile onset glaucoma

Clinical feature: 

Definition: Hereditary glaucoma is a heterogenous group of diseases with elevated intraocular pressure. It occurs with open angle. Juvenile and late onset forms can be distinguished.

Pathogenesis: As this group is heterogenous different pathogenetic mechanisms can be separated. Different types of inheritance are possible as well.

Diagnostics: 

Strategy: If glaucoma is congenital or hereditary, molecular diagnostic could be considered.

Systematic link table: 

Hereditary ocular disease and visual impairment
Juvenile onset glaucoma
CYP1B1
LMX1B
MYOC

Literature: 

Alward WL et al. (1998) Clinical features associated with mutations in the chromosome 1 open-angle glaucoma gene (GLC1A)
Stoilova D et al. (1996) Localization of a locus (GLC1B) for adult-onset primary open angle glaucoma to the 2cen-q13 region.