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Hereditary diseases of the hematopoetic system and coagulopathies


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Hereditary diseases of the hematopoetic system and coagulopathies

Clinical feature: 

Definition: This large group of familial haematological diseases includes disorders in all blood cell lines and coagulation factors.

Systematic link table: 

Hereditary diseases
HIV resistance
CCR5
Hereditary bone disease
Hereditary broncho-pulmonary disease
Hereditary endocrinological diseases
Hereditary kidney diseases
Hereditary metabolic diseases
Hereditary neurological disorders
Hereditary ocular disease and visual impairment
Hereditary vascular disease
Hypertension
ACE
ACE2
AGT
hereditary diseases of the hematopoetic system and coagulopathies
Hereditary bleeding disorders
Disturbances of vitamin K metabolism
Combined deficiency of vitamin K-dependent clotting factors type 1
GGCX
Combined deficiency of vitamin K-dependent clotting factors type 2
VKORC1
Coumarin resistance
CYP2A6
CYP2C9
CYP4F2
VKORC1
Inherited disorders of platelets
Alloimmune thrombocytopenia
ITGA2B
ITGB3
Bernard-Soulier syndrome
GP1BA
GP1BB
GP9
Thrombasthenia of Glanzmann and Naegeli
ITGA2B
ITGB3
Ovalocytosis
SLC4A1
Paroxysmal nocturnal hemoglobinuria
PIGA
Thromboembolic diseases
F2
F5
HABP2
MTHFR
PROC
PROS1
SERPINC1
THBD
VKORC1

Literature: 

Herzog RW et al. (2003) Update on gene therapy for hereditary hematological disorders.
Herzog RW et al. (2001) Gene therapy for hereditary hematological disorders.
Finsterer J et al. (2007) Hematological manifestations of primary mitochondrial disorders.
Tatlisumak T et al. (1996) Hematologic disorders associated with ischemic stroke.
Tatlisumak T et al. (1996) Hematologic disorders associated with ischemic stroke.