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MODY8 diabetes
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MODY8 diabetes

Clinical feature: 

Definition: MODY8 is an autosomal dominant early-onset type 2 diabetes caused by mutations of the CEL gene.

Diagnostics: 

Differential: All know types of MODY diabetes are characterized by autosomal dominant inheritance, primary non-insulin-dependence, and manifestation in young age (mostly before 25 years of age)  » » » 
   The clinical course of MODY2 diabetes varies in that it remains non-insulin-dependent.  » » » 

Systematic link table: 

MODY diabetes
MODY1 diabetes
HNF4A
MODY10 diabetes
INS
MODY2 diabetes
GCK
MODY3 diabetes
HNF1A
MODY4 diabetes
PDX1
MODY5 diabetes
HNF1B
MODY6 diabetes
NEUROD1
MODY7 diabetes
KLF11
MODY8 diabetes
CEL
MODY9 diabetes
PAX4

Literature: 

Hardt PD et al. (2003) High prevalence of exocrine pancreatic insufficiency in diabetes mellitus. A multicenter study screening fecal elastase 1 concentrations in 1,021 diabetic patients.
Raeder H et al. (2006) Mutations in the CEL VNTR cause a syndrome of diabetes and pancreatic exocrine dysfunction.