MODY diabetes

MODY diabetes is the autosomal dominant form of type 2 diabetes.

Test Strategy

The following criteria are essential for the diagnosis of MODY diabetes:1. juvenile onset of diabetes.2. primarily no insulin dependency.3. autosomal dominant inheritance.4. confirmation by molecular test.

Pathogenesis

Genes controlling insulin secretion are responsible for this kind of diabetes. Which way also insulin sensitivity is diminished is not clear yet.

Systematic

Diabetes mellitus
	Diabetic nephropathy
	Diabetic retinopathy
	Gestational diabetes mellitus
	Hereditary susceptibility to diabetes
	Insulin resistance
	MODY diabetes
		MODY1 diabetes
			HNF4A
		MODY10 diabetes
			INS
		MODY11 diabetes
			BLK
		MODY12 diabetes
			ABCC8
		MODY13 diabetes
			KCNJ11
		MODY14 diabetes
			APPL1
		MODY2 diabetes
			GCK
		MODY3 diabetes
			HNF1A
		MODY4 diabetes
			PDX1
		MODY5 diabetes
			HNF1B
		MODY6 diabetes
			NEUROD1
		MODY7 diabetes
			KLF11
		MODY8 diabetes
			CEL
		MODY9 diabetes
			PAX4
	Mitochondrial diabetes
	Neonatal diabetes mellitus
	Noninsulin-dependent diabetes mellitus 1
	Pancreatogenic diabetes
	Severe obesity and type 2 diabetes
	Susceptibility to type 1 diabetes 01