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Monogenic hypertension


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Monogenic hypertension

Clinical feature: 

Definition: Monogenic hypertension is caused by alteration of a single gene and therefore shows Mendelian patterns of inheritance.

Epidemiology: Mendelian forms of hypertension are rare. They account for less than 1%.

Systematic link table: 

Hypertension
ACE
ACE2
AGT
Monogenic hypertension
Apparent mineralocorticoid excess
HSD11B2
Glucocorticoid-remediable aldosteronism
CYP11B1
CYP11B2
Liddle syndrome
NEDD4
NEDD4L
NR3C2
SCNN1B
SCNN1G
Pseudohypoaldosteronism
Pseudohypoaldosteronism type 2
WNK1
WNK4
Pseudohypoaldosteronism type1
NR3C2
SCNN1A
SCNN1B
SCNN1G

Literature: 

Luft FC et al. (2004) Present status of genetic mechanisms in hypertension.