Clinical feature: 

Definition: MPGN is a rate type of glomerulonephritis with typical immunohistochemical findings. This disease often is associated with typical genetic findings.

Literature: 

Berry PL et al. (1981) Membranoproliferative glomerulonephritis in two sibships.
Habib R et al. () Idiopathic membranoproliferative glomerulonephritis in children. Report of 105 cases.
Mandalenakis N et al. (1971) Lobular glomerulonephritis and membranoproliferative glomerulonephritis: a clinical and pathologic study based on renal biopsies.
Strife CF et al. (1977) Membranoproliferative glomerulonephritis with disruption of the glomerular basement membrane.
Stutchfield PR et al. (1986) X-linked mesangiocapillary glomerulonephritis.
Abrera-Abeleda MA et al. (2006) Variations in the complement regulatory genes factor H (CFH) and factor H related 5 (CFHR5) are associated with membranoproliferative glomerulonephritis type II (dense deposit disease).
Appel GB et al. (2005) Membranoproliferative glomerulonephritis type II (dense deposit disease): an update.
Ault BH et al. (2000) Factor H and the pathogenesis of renal diseases.
Ault BH et al. (1997) Human factor H deficiency. Mutations in framework cysteine residues and block in H protein secretion and intracellular catabolism.
Brai M et al. (1988) Combined homozygous factor H and heterozygous C2 deficiency in an Italian family.
Dragon-Durey MA et al. (2004) Heterozygous and homozygous factor h deficiencies associated with hemolytic uremic syndrome or membranoproliferative glomerulonephritis: report and genetic analysis of 16 cases.
Fijen CA et al. (1996) Heterozygous and homozygous factor H deficiency states in a Dutch family.
Hegasy GA et al. (2002) The molecular basis for hereditary porcine membranoproliferative glomerulonephritis type II: point mutations in the factor H coding sequence block protein secretion.
Høgåsen K et al. (1995) Hereditary porcine membranoproliferative glomerulonephritis type II is caused by factor H deficiency.
Levy M et al. (1986) H deficiency in two brothers with atypical dense intramembranous deposit disease.
Licht C et al. (2006) Deletion of Lys224 in regulatory domain 4 of Factor H reveals a novel pathomechanism for dense deposit disease (MPGN II).
Pickering MC et al. (2002) Uncontrolled C3 activation causes membranoproliferative glomerulonephritis in mice deficient in complement factor H.
Rougier N et al. (1998) Human complement factor H deficiency associated with hemolytic uremic syndrome.
Sánchez-Corral P et al. (2000) Molecular basis for factor H and FHL-1 deficiency in an Italian family.
Saunders RE et al. (2006) An interactive web database of factor H-associated hemolytic uremic syndrome mutations: insights into the structural consequences of disease-associated mutations.
Servais A et al. (2007) Primary glomerulonephritis with isolated C3 deposits: a new entity which shares common genetic risk factors with haemolytic uraemic syndrome.
Vogt BA et al. (1995) Inherited factor H deficiency and collagen type III glomerulopathy.
Welch TR et al. (2002) Complement in glomerulonephritis.
Wyatt RJ et al. (1982) Partial H (beta 1H) deficiency and glomerulonephritis in two families.
Abrera-Abeleda MA et al. (2006) Variations in the complement regulatory genes factor H (CFH) and factor H related 5 (CFHR5) are associated with membranoproliferative glomerulonephritis type II (dense deposit disease).
McRae JL et al. (2001) Human factor H-related protein 5 (FHR-5). A new complement-associated protein.
McRae JL et al. (2002) Location and structure of the human FHR-5 gene.