Membranoproliferative glomerulonephritis 305800
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Clinical feature:
Definition: MPGN is a rate type of glomerulonephritis with typical immunohistochemical findings. This disease often is associated with typical genetic findings.
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Literature:
Berry PL et al. (1981) Membranoproliferative glomerulonephritis in two sibships. Habib R et al. () Idiopathic membranoproliferative glomerulonephritis in children. Report of 105 cases. Mandalenakis N et al. (1971) Lobular glomerulonephritis and membranoproliferative glomerulonephritis: a clinical and pathologic study based on renal biopsies. Strife CF et al. (1977) Membranoproliferative glomerulonephritis with disruption of the glomerular basement membrane. Stutchfield PR et al. (1986) X-linked mesangiocapillary glomerulonephritis. Abrera-Abeleda MA et al. (2006) Variations in the complement regulatory genes factor H (CFH) and factor H related 5 (CFHR5) are associated with membranoproliferative glomerulonephritis type II (dense deposit disease). Appel GB et al. (2005) Membranoproliferative glomerulonephritis type II (dense deposit disease): an update. Ault BH et al. (2000) Factor H and the pathogenesis of renal diseases. Ault BH et al. (1997) Human factor H deficiency. Mutations in framework cysteine residues and block in H protein secretion and intracellular catabolism. Brai M et al. (1988) Combined homozygous factor H and heterozygous C2 deficiency in an Italian family. Dragon-Durey MA et al. (2004) Heterozygous and homozygous factor h deficiencies associated with hemolytic uremic syndrome or membranoproliferative glomerulonephritis: report and genetic analysis of 16 cases. Fijen CA et al. (1996) Heterozygous and homozygous factor H deficiency states in a Dutch family. Hegasy GA et al. (2002) The molecular basis for hereditary porcine membranoproliferative glomerulonephritis type II: point mutations in the factor H coding sequence block protein secretion. Høgåsen K et al. (1995) Hereditary porcine membranoproliferative glomerulonephritis type II is caused by factor H deficiency. Levy M et al. (1986) H deficiency in two brothers with atypical dense intramembranous deposit disease. Licht C et al. (2006) Deletion of Lys224 in regulatory domain 4 of Factor H reveals a novel pathomechanism for dense deposit disease (MPGN II). Pickering MC et al. (2002) Uncontrolled C3 activation causes membranoproliferative glomerulonephritis in mice deficient in complement factor H. Rougier N et al. (1998) Human complement factor H deficiency associated with hemolytic uremic syndrome. Sánchez-Corral P et al. (2000) Molecular basis for factor H and FHL-1 deficiency in an Italian family. Saunders RE et al. (2006) An interactive web database of factor H-associated hemolytic uremic syndrome mutations: insights into the structural consequences of disease-associated mutations. Servais A et al. (2007) Primary glomerulonephritis with isolated C3 deposits: a new entity which shares common genetic risk factors with haemolytic uraemic syndrome. Vogt BA et al. (1995) Inherited factor H deficiency and collagen type III glomerulopathy. Welch TR et al. (2002) Complement in glomerulonephritis. Wyatt RJ et al. (1982) Partial H (beta 1H) deficiency and glomerulonephritis in two families. Abrera-Abeleda MA et al. (2006) Variations in the complement regulatory genes factor H (CFH) and factor H related 5 (CFHR5) are associated with membranoproliferative glomerulonephritis type II (dense deposit disease). McRae JL et al. (2001) Human factor H-related protein 5 (FHR-5). A new complement-associated protein. McRae JL et al. (2002) Location and structure of the human FHR-5 gene.