Laboratory for Molecular Diagnostics
Center for Nephrology and Metabolic Disorders
The disorder is caused by a premature stop codon (p.R387X), and is characterized by elevated prorenin plasma levels, which pathophysiological consequences are yet to be determined.
Hypertension
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ACE
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ACE2
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AGT
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Benign hyperproreninemia
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REN
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Monogenic hypertension
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Preeclampsia
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Salt-sensitive essential hypertension
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VEGFC
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