Transient neonatal diabetes mellitus 2

Transient neonatal diabetes mellitus is an autosomal dominant disorder caused by mutations of the ABCC8 gene. The clinical variation within a family can vary significantly from transient or permanent neonatal diabetes mellitus to a typical type 2 diabetes of adulthood.

Pathogenesis

The disease is cause by an activating mutation of the ABCC8 gene.

Management

The disease can be treated by sulfonyl urea.

Systematic

Neonatal diabetes mellitus
	Leprechaunism
	Mitchell-Riley syndrome
	Neonatal diabetes mellitus with congenital hypothyroidism
	Pancreatogenic diabetes
	Permanent neonatal diabetes mellitus
	Rabson-Mendenhall syndrome
	Renal cysts and diabetes (RCAD)
	Transient neonatal diabetes mellitus 1
	Transient neonatal diabetes mellitus 2
		ABCC8
	Transient neonatal diabetes mellitus 3
	X-linked immunodysregulation, polyendocrinopathy, and enteropathy