Scientific background:

Summary: The AGTR1 gene encodes the angiotensin receptor 1 which is involved in signal transduction regulation blood pressure and electrolyt balance. Also during kidney development the renin angiotensin system plays a role.

Methodology:

Literature: 

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AbdAlla S et al. (2000) AT1-receptor heterodimers show enhanced G-protein activation and altered receptor sequestration.
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