Cytochrome P450, family 2, subfamily A, polypeptide 6

This gene, CYP2A6, encodes a member of the cytochrome P450 superfamily of enzymes. Among the pharmaceutical that are metabolized by that enzyme is coumarine. Also nikotine is metabolized by that enzyme, so it is not surprising that genetic variants may be associated with lung cancer susceptibility.

Genetests:

Clinic	Method	Massive parallel sequencing
	Turnaround	25 days
	Specimen type	genomic DNA

Research	Method	Genomic sequencing of the entire coding region
	Turnaround	25 days
	Specimen type	genomic DNA

Research	Method	Multiplex Ligation-Dependent Probe Amplification
	Turnaround	25 days
	Specimen type	genomic DNA

Related Diseases:

Coumarin resistance
	CYP2A6
	CYP2C9
	CYP4F2
	VKORC1

Update:

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