Die nicht-autoimmunbedingte Hyperthyreose ist eine autosomal dominante Erkrankung, die durch aktivierende Mutationen im TSHR-Gen hervorgerufen wird.
Hyperthyreose | ||||
Basedow-Krankheit | ||||
Familiäre Schwangerschaftshyperthyreose | ||||
McCune-Albright-Syndrom | ||||
Neigung zur thyreotoxischen periodischen Paralyse 1 | ||||
Nicht-autoimmunbedingte Hyperthyreose | ||||
TSHR | ||||
1. |
Paschke R et al. (1997) The thyrotropin receptor in thyroid diseases. |
2. |
Thomas JS et al. (1982) Familial hyperthyroidism without evidence of autoimmunity. |
3. |
Kopp P et al. (1995) Brief report: congenital hyperthyroidism caused by a mutation in the thyrotropin-receptor gene. |
4. |
Duprez L et al. (1994) Germline mutations in the thyrotropin receptor gene cause non-autoimmune autosomal dominant hyperthyroidism. |
5. |
de Roux N et al. (1996) A neomutation of the thyroid-stimulating hormone receptor in a severe neonatal hyperthyroidism. |
6. |
Hollingsworth DR et al. (1976) Congenital graves disease. Four familial cases with long-term follow-up and perspective. |
7. |
Hollingsworth DR et al. (1972) Hereditary aspects of Graves' disease in infancy and childhood. |
8. |
Orphanet article Orphanet ID 424 |
9. |
OMIM.ORG article Omim 609152 |