PDCD1-Gen

Lázár-Molnár E et al. (2008) The PD-1/PD-L costimulatory pathway critically affects host resistance to the pathogenic fungus Histoplasma capsulatum.

Sugiura D et al. (2019) {'i': ['cis'], 'content': 'Restriction of PD-1 function by -PD-L1/CD80 interactions is required for optimal T cell responses.'}

Meng X et al. (2018) FBXO38 mediates PD-1 ubiquitination and regulates anti-tumour immunity of T cells.

Wartewig T et al. (2017) PD-1 is a haploinsufficient suppressor of T cell lymphomagenesis.

Le DT et al. (2017) Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade.

Gordon SR et al. (2017) PD-1 expression by tumour-associated macrophages inhibits phagocytosis and tumour immunity.

George S et al. (2017) Loss of PTEN Is Associated with Resistance to Anti-PD-1 Checkpoint Blockade Therapy in Metastatic Uterine Leiomyosarcoma.

Sen DR et al. (2016) The epigenetic landscape of T cell exhaustion.

Pauken KE et al. (2016) Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade.

Yang W et al. (2013) Increased expression of programmed death (PD)-1 and its ligand PD-L1 correlates with impaired cell-mediated immunity in high-risk human papillomavirus-related cervical intraepithelial neoplasia.

Kawamoto S et al. (2012) The inhibitory receptor PD-1 regulates IgA selection and bacterial composition in the gut.

Quigley M et al. (2010) Transcriptional analysis of HIV-specific CD8+ T cells shows that PD-1 inhibits T cell function by upregulating BATF.

Dai H et al. (2010) Cutting edge: programmed death-1 defines CD8+CD122+ T cells as regulatory versus memory T cells.

Said EA et. al. (2010) Programmed death-1-induced interleukin-10 production by monocytes impairs CD4+ T cell activation during HIV infection.

Day CL et al. (2006) PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression.

Barber DL et al. (2006) Restoring function in exhausted CD8 T cells during chronic viral infection.

Okazaki T et al. (2005) Hydronephrosis associated with antiurothelial and antinuclear autoantibodies in BALB/c-Fcgr2b-/-Pdcd1-/- mice.

Kroner A et al. (2005) A PD-1 polymorphism is associated with disease progression in multiple sclerosis.

Okazaki T et al. (2003) Autoantibodies against cardiac troponin I are responsible for dilated cardiomyopathy in PD-1-deficient mice.

Prokunina L et al. (2002) A regulatory polymorphism in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humans.

Latchman Y et al. (2001) PD-L2 is a second ligand for PD-1 and inhibits T cell activation.

Nishimura H et al. (2001) Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice.

Freeman GJ et al. (2000) Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation.

Finger LR et al. (1997) The human PD-1 gene: complete cDNA, genomic organization, and developmentally regulated expression in B cell progenitors.

Shinohara T et al. (1994) Structure and chromosomal localization of the human PD-1 gene (PDCD1).

Ishida Y et al. (1992) Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death.