The deficiency of mannose-binding protein caused by mutations of the MBL2 gene is not a disease itself, but an association with chronic inflammatory diseases and gestational diabetes is observed.
Mannose-binding protein deficiency is observed in 5% of European ancestry and even 10% of sub-Saharan Africans.
A protein level less than 100 ng/ml is considered a deficiency.
Gestational diabetes mellitus | ||||
MODY diabetes | ||||
Mannose-binding protein deficiency | ||||
MBL2 | ||||
Mitchell-Riley syndrome | ||||
Partial lipodystrophy | ||||
Susceptibility to type 1 diabetes 01 | ||||
TRPM6 | ||||
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OMIM.ORG article Omim 614372 |