Hyperzincemia and hypercalprotectinemia

Hyperzincemia and hypercalprotectinemia is an autosomal dominant autoinflammatory disease caused by mutations of the PSTPIP1. Like PAPA syndrome pyogenic arthritis, pyoderma gangrenosum, and acne are found in addition to elevated zinc levels in plasma.

Systematic

Hereditary metabolic diseases
	Coenzyme Q10 deficiency
	Congenital disorder of glycosylation
	Disorders of cobalamin metabolism
	Disorders of iron metabolism
	Disorders of urate metabolism
	Disturbances in phosphate metabolism
	Disturbances of glucose metabolism
	Food intolerance
	Genetic hyperbilirubinemia
	Glycolipidosis
	HADH deficiency
	Hereditary disorders protein metabolism
	Hereditary lipid disorders
	Hypercatabolic hypoproteinemia
	Hyperzincemia and hypercalprotectinemia
		PSTPIP1
	Hypomagnesemia
	Hypomethylation syndrome
	Lysosomal storage disease
	MELAS syndrome
	Methionine adenosyltransferase deficiency
	Methylmalonic aciduria
	Urea cycle disorders

References:

1.	Smith JC et. al. (1976) Elevated plasmz zinc: a heritable anomaly.

2.	Hambidge KM et. al. (1985) Hyperzincemia in a patient with pyoderma gangrenosum.

3.	Failla ML et. al. (1982) Characterization of zinc-binding proteins of plasma in familial hyperzincemia.

4.	Sampson B et. al. (1997) A case of hyperzincemia with functional zinc depletion: a new disorder?

5.	Saito Y et. al. (2002) Hyperzincemia with systemic inflammation: a heritable disorder of calprotectin metabolism with rheumatic manifestations?

6.	Sampson B et. al. (2002) Hyperzincaemia and hypercalprotectinaemia: a new disorder of zinc metabolism.

7.	Stewart AJ et. al. (2003) Interdomain zinc site on human albumin.

Update: Aug. 14, 2020

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