Psoriasis is quite heritable. It is associated with various loci throughout the genome. The type 3 susceptibility is associates with 4q.
1. |
Nair RP et al. (1997) Evidence for two psoriasis susceptibility loci (HLA and 17q) and two novel candidate regions (16q and 20p) by genome-wide scan. |
3. |
Matthews D et al. (1996) Evidence that a locus for familial psoriasis maps to chromosome 4q. |
4. |
Liu Y et al. (2008) A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci. |
5. |
Caruso R et al. (2009) Involvement of interleukin-21 in the epidermal hyperplasia of psoriasis. |