IL17F gene
The gene encodes interleukin-17F, a cytokine that is expressed by activated T cells and is involved n various processes of immun regulation. Mutations are associated with candidiasis type 6.
Genetests:
Related Diseases:
References:
1. |
McAllister F et al. (2005) Role of IL-17A, IL-17F, and the IL-17 receptor in regulating growth-related oncogene-alpha and granulocyte colony-stimulating factor in bronchial epithelium: implications for airway inflammation in cystic fibrosis.
|
2. |
Toy D et al. (2006) Cutting edge: interleukin 17 signals through a heteromeric receptor complex.
|
3. |
Kudva A et al. (2011) Influenza A inhibits Th17-mediated host defense against bacterial pneumonia in mice.
|
4. |
Puel A et al. (2011) Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17 immunity.
|
5. |
Starnes T et al. (2001) Cutting edge: IL-17F, a novel cytokine selectively expressed in activated T cells and monocytes, regulates angiogenesis and endothelial cell cytokine production.
|
6. |
Kawaguchi M et al. (2001) Identification of a novel cytokine, ML-1, and its expression in subjects with asthma.
|
7. |
Hurst SD et al. (2002) New IL-17 family members promote Th1 or Th2 responses in the lung: in vivo function of the novel cytokine IL-25.
|
8. |
Wang X et al. (2012) Transcription of Il17 and Il17f is controlled by conserved noncoding sequence 2.
|
Update: Aug. 14, 2020