IRF5 gene

Akilesh HM et al. (2019) Chronic TLR7 and TLR9 signaling drives anemia via differentiation of specialized hemophagocytes.

Taniguchi T et al. (2001) IRF family of transcription factors as regulators of host defense.

Barnes BJ et al. (2001) Virus-specific activation of a novel interferon regulatory factor, IRF-5, results in the induction of distinct interferon alpha genes.

Barnes BJ et al. (2002) Multiple regulatory domains of IRF-5 control activation, cellular localization, and induction of chemokines that mediate recruitment of T lymphocytes.

Morley M et al. (2004) Genetic analysis of genome-wide variation in human gene expression.

Sigurdsson S et al. (2005) Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus.

Takaoka A et al. (2005) Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors.

Graham RR et al. (2006) A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus.

Cunninghame Graham DS et al. (2007) Association of IRF5 in UK SLE families identifies a variant involved in polyadenylation.

Yanai H et al. (2007) Role of IFN regulatory factor 5 transcription factor in antiviral immunity and tumor suppression.

Kozyrev SV et al. (2007) Structural insertion/deletion variation in IRF5 is associated with a risk haplotype and defines the precise IRF5 isoforms expressed in systemic lupus erythematosus.

Reddy MV et al. (2007) Genetic association of IRF5 with SLE in Mexicans: higher frequency of the risk haplotype and its homozygozity than Europeans.

Sigurdsson S et. al. (2007) Association of a haplotype in the promoter region of the interferon regulatory factor 5 gene with rheumatoid arthritis.

Dideberg V et al. (2007) An insertion-deletion polymorphism in the interferon regulatory Factor 5 (IRF5) gene confers risk of inflammatory bowel diseases.

Sigurdsson S et al. (2008) Comprehensive evaluation of the genetic variants of interferon regulatory factor 5 (IRF5) reveals a novel 5 bp length polymorphism as strong risk factor for systemic lupus erythematosus.

Couzinet A et al. (2008) A cell-type-specific requirement for IFN regulatory factor 5 (IRF5) in Fas-induced apoptosis.