TGF-beta receptor type-2

Ozdamar B et al. (2005) Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity.

Li S et al. (2020) Cancer immunotherapy via targeted TGF-β signalling blockade in T cells.

Lin HY et al. (1992) Expression cloning of the TGF-beta type II receptor, a functional transmembrane serine/threonine kinase.

Liu M et al. (2020) TGF-β suppresses type 2 immunity to cancer.

Lu SL et al. (1998) HNPCC associated with germline mutation in the TGF-beta type II receptor gene.

Markowitz S et al. (1995) Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability.

Mathew S et al. (1994) Transforming growth factor receptor gene TGFBR2 maps to human chromosome band 3p22.

Mizuguchi T et al. (2004) Heterozygous TGFBR2 mutations in Marfan syndrome.

Myeroff LL et al. (1995) A transforming growth factor beta receptor type II gene mutation common in colon and gastric but rare in endometrial cancers with microsatellite instability.

Neptune ER et al. (2003) Dysregulation of TGF-beta activation contributes to pathogenesis in Marfan syndrome.

Li MO et al. (2006) Transforming growth factor-beta controls development, homeostasis, and tolerance of T cells by regulatory T cell-dependent and -independent mechanisms.

Pannu H et al. (2005) Mutations in transforming growth factor-beta receptor type II cause familial thoracic aortic aneurysms and dissections.

Parsons R et al. (1995) Microsatellite instability and mutations of the transforming growth factor beta type II receptor gene in colorectal cancer.

Sanford LP et al. (1997) TGFbeta2 knockout mice have multiple developmental defects that are non-overlapping with other TGFbeta knockout phenotypes.

Souza RF et al. (1996) Microsatellite instability in the insulin-like growth factor II receptor gene in gastrointestinal tumours.

Takenoshita S et al. (1996) The genomic structure of the gene encoding the human transforming growth factor beta type II receptor (TGF-beta RII).

Tanaka S et al. (2000) A dominant negative mutation of transforming growth factor-beta receptor type II gene in microsatellite stable oesophageal carcinoma.

Tannergård P et al. (1997) Tumorigenesis in colorectal tumors from patients with hereditary non-polyposis colorectal cancer.

Tooley MJ et al. (2017) Extreme phenotypes of Loeys Dietz syndrome.

Watanabe T et al. (2001) Molecular predictors of survival after adjuvant chemotherapy for colon cancer.

Eshleman JR et al. (1995) Microsatellite instability in inherited and sporadic neoplasms.

De Paepe A et al. (1996) Revised diagnostic criteria for the Marfan syndrome.

Loeys BL et al. (2005) A syndrome of altered cardiovascular, craniofacial, neurocognitive and skeletal development caused by mutations in TGFBR1 or TGFBR2.

Loeys BL et al. (2006) Aneurysm syndromes caused by mutations in the TGF-beta receptor.

Singh KK et al. (2006) TGFBR1 and TGFBR2 mutations in patients with features of Marfan syndrome and Loeys-Dietz syndrome.

Azhar M et al. (2003) Transforming growth factor beta in cardiovascular development and function.

Boileau C et al. (1993) Autosomal dominant Marfan-like connective-tissue disorder with aortic dilation and skeletal anomalies not linked to the fibrillin genes.

Bonyadi M et al. (1996) The TGF beta type II receptor, Tgfbr2, maps to distal mouse chromosome 9.

Chen RH et al. (1993) Inactivation of the type II receptor reveals two receptor pathways for the diverse TGF-beta activities.

Disabella E et al. (2006) Two novel and one known mutation of the TGFBR2 gene in Marfan syndrome not associated with FBN1 gene defects.

Tesseur I et al. (2006) Deficiency in neuronal TGF-beta signaling promotes neurodegeneration and Alzheimer's pathology.

Fakhro KA et al. (2011) Rare copy number variations in congenital heart disease patients identify unique genes in left-right patterning.

Grady WM et al. (1999) Mutational inactivation of transforming growth factor beta receptor type II in microsatellite stable colon cancers.

Hahm KB et al. (1999) Repression of the gene encoding the TGF-beta type II receptor is a major target of the EWS-FLI1 oncoprotein.

Han G et al. (2005) Distinct mechanisms of TGF-beta1-mediated epithelial-to-mesenchymal transition and metastasis during skin carcinogenesis.

Hasham SN et al. (2003) Mapping a locus for familial thoracic aortic aneurysms and dissections (TAAD2) to 3p24-25.

Ito Y et al. (2003) Conditional inactivation of Tgfbr2 in cranial neural crest causes cleft palate and calvaria defects.

Kirmani S et al. (2010) Germline TGF-beta receptor mutations and skeletal fragility: a report on two patients with Loeys-Dietz syndrome.

Kosaki K et al. (2006) Molecular pathology of Shprintzen-Goldberg syndrome.

Law C et al. (2006) Clinical features in a family with an R460H mutation in transforming growth factor beta receptor 2 gene.