MyD88-Gen

Conway DH et al. (2010) Myeloid differentiation primary response gene 88 (MyD88) deficiency in a large kindred.

Gavin AL et al. (2006) Adjuvant-enhanced antibody responses in the absence of toll-like receptor signaling.

Brown SL et al. (2007) Myd88-dependent positioning of Ptgs2-expressing stromal cells maintains colonic epithelial proliferation during injury.

Chen CJ et al. (2007) Identification of a key pathway required for the sterile inflammatory response triggered by dying cells.

Rakoff-Nahoum S et al. (2007) Regulation of spontaneous intestinal tumorigenesis through the adaptor protein MyD88.

LaRosa DF et al. (2008) T cell expression of MyD88 is required for resistance to Toxoplasma gondii.

Cirl C et al. (2008) Subversion of Toll-like receptor signaling by a unique family of bacterial Toll/interleukin-1 receptor domain-containing proteins.

von Bernuth H et al. (2008) Pyogenic bacterial infections in humans with MyD88 deficiency.

Wen L et al. (2008) Innate immunity and intestinal microbiota in the development of Type 1 diabetes.

Lin SC et al. (2010) Helical assembly in the MyD88-IRAK4-IRAK2 complex in TLR/IL-1R signalling.

Kagan JC et al. (2006) Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling.

Picard C et al. (2010) Clinical features and outcome of patients with IRAK-4 and MyD88 deficiency.

Ngo VN et al. (2011) Oncogenically active MYD88 mutations in human lymphoma.

Tarallo V et al. (2012) DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88.

Treon SP et al. (2012) MYD88 L265P somatic mutation in Waldenström's macroglobulinemia.

Zhu W et al. (2012) Interleukin receptor activates a MYD88-ARNO-ARF6 cascade to disrupt vascular stability.

Landgren O et al. (2012) MYD88 L265P somatic mutation in IgM MGUS.

Zhang D et al. (2015) Neutrophil ageing is regulated by the microbiome.

Phelan JD et al. (2018) A multiprotein supercomplex controlling oncogenic signalling in lymphoma.

Platt CD et al. (2019) A novel truncating mutation in MYD88 in a patient with BCG adenitis, neutropenia and delayed umbilical cord separation.

Takeuchi O et al. (2000) Cutting edge: TLR2-deficient and MyD88-deficient mice are highly susceptible to Staphylococcus aureus infection.

Zhande R et al. (2007) FADD negatively regulates lipopolysaccharide signaling by impairing interleukin-1 receptor-associated kinase 1-MyD88 interaction.

Diebold SS et al. (2004) Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA.

Lord KA et al. (1990) Complexity of the immediate early response of myeloid cells to terminal differentiation and growth arrest includes ICAM-1, Jun-B and histone variants.

Bonnert TP et al. (1997) The cloning and characterization of human MyD88: a member of an IL-1 receptor related family.

Hardiman G et al. (1997) Genetic structure and chromosomal mapping of MyD88.

Muzio M et al. (1997) IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling.

Adachi O et al. (1998) Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function.

Medzhitov R et al. (1998) MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways.

Kawai T et al. (1999) Unresponsiveness of MyD88-deficient mice to endotoxin.

Pasare C et al. (2005) Control of B-cell responses by Toll-like receptors.

Hayashi F et al. (2001) The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5.

Jankovic D et al. (2002) In the absence of IL-12, CD4(+) T cell responses to intracellular pathogens fail to default to a Th2 pattern and are host protective in an IL-10(-/-) setting.

Burns K et al. (2003) Inhibition of interleukin 1 receptor/Toll-like receptor signaling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4.

Bellocchio S et al. (2004) The contribution of the Toll-like/IL-1 receptor superfamily to innate and adaptive immunity to fungal pathogens in vivo.

Skerrett SJ et al. (2004) Cutting edge: myeloid differentiation factor 88 is essential for pulmonary host defense against Pseudomonas aeruginosa but not Staphylococcus aureus.

Björkbacka H et al. (2004) Reduced atherosclerosis in MyD88-null mice links elevated serum cholesterol levels to activation of innate immunity signaling pathways.

Blander JM et al. (2004) Regulation of phagosome maturation by signals from toll-like receptors.

Fremond CM et al. (2004) Fatal Mycobacterium tuberculosis infection despite adaptive immune response in the absence of MyD88.

Jiang D et al. (2005) Regulation of lung injury and repair by Toll-like receptors and hyaluronan.