Susceptibility to vascular dementia ay be caused by genetic factors.
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38. |
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40. |
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41. |
Nadel S et al. (1996) Variation in the tumor necrosis factor-alpha gene promoter region may be associated with death from meningococcal disease. |
42. |
van Hensbroek MB et al. (1996) The effect of a monoclonal antibody to tumor necrosis factor on survival from childhood cerebral malaria. |
43. |
Black RA et al. (1997) A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells. |
44. |
Conway DJ et al. (1997) Scarring trachoma is associated with polymorphism in the tumor necrosis factor alpha (TNF-alpha) gene promoter and with elevated TNF-alpha levels in tear fluid. |
45. |
Wilson AG et al. (1997) Effects of a polymorphism in the human tumor necrosis factor alpha promoter on transcriptional activation. |
46. |
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47. |
Marino MW et al. (1997) Characterization of tumor necrosis factor-deficient mice. |
48. |
Roy S et al. (1997) Tumor necrosis factor promoter polymorphism and susceptibility to lepromatous leprosy. |
49. |
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50. |
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51. |
Ma JJ et al. (1998) Genetic contribution of the tumor necrosis factor region in Guillain-Barré syndrome. |
52. |
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53. |
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54. |
Knight JC et al. (1999) A polymorphism that affects OCT-1 binding to the TNF promoter region is associated with severe malaria. |
56. |
Ruuls SR et al. (1999) Unlinking tumor necrosis factor biology from the major histocompatibility complex: lessons from human genetics and animal models. |
57. |
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58. |
Mira JP et al. (1999) Association of TNF2, a TNF-alpha promoter polymorphism, with septic shock susceptibility and mortality: a multicenter study. |
61. |
Winchester EC et al. (2000) Association of the TNF-alpha-308 (G-->A) polymorphism with self-reported history of childhood asthma. |
62. |
Ota N et al. (2000) Linkage of human tumor necrosis factor-alpha to human osteoporosis by sib pair analysis. |
63. |
Koss K et al. (2000) Cytokine (TNF alpha, LT alpha and IL-10) polymorphisms in inflammatory bowel diseases and normal controls: differential effects on production and allele frequencies. |
66. |
Rosmond R et al. (2001) G-308A polymorphism of the tumor necrosis factor alpha gene promoter and salivary cortisol secretion. |
67. |
Escobar-Morreale HF et al. (2001) TNF-alpha and hyperandrogenism: a clinical, biochemical, and molecular genetic study. |
68. |
Quasney MW et al. (2001) Increased frequency of the tumor necrosis factor-alpha-308 A allele in adults with human immunodeficiency virus dementia. |
69. |
Keane J et al. (2001) Tuberculosis associated with infliximab, a tumor necrosis factor alpha-neutralizing agent. |
70. |
Beattie EC et al. (2002) Control of synaptic strength by glial TNFalpha. |
71. |
Roach DR et al. (2002) TNF regulates chemokine induction essential for cell recruitment, granuloma formation, and clearance of mycobacterial infection. |
72. |
Gorman JD et al. (2002) Treatment of ankylosing spondylitis by inhibition of tumor necrosis factor alpha. |
73. |
van Heel DA et al. (2002) Inflammatory bowel disease is associated with a TNF polymorphism that affects an interaction between the OCT1 and NF(-kappa)B transcription factors. |
75. |
Krikovszky D et al. (2002) Association between G-308A polymorphism of the tumor necrosis factor-alpha gene and 24-hour ambulatory blood pressure values in type 1 diabetic adolescents. |
76. |
García-Ruiz C et al. (2003) Defective TNF-alpha-mediated hepatocellular apoptosis and liver damage in acidic sphingomyelinase knockout mice. |
77. |
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78. |
Takahashi JL et al. (2003) Interleukin-1beta promotes oligodendrocyte death through glutamate excitotoxicity. |
79. |
Balding J et al. (2003) Cytokine gene polymorphisms: association with psoriatic arthritis susceptibility and severity. |
80. |
Shbaklo H et al. (2003) No association between the -1031 polymorphism in the TNF-alpha promoter region and type 1 diabetes. |
82. |
Kim YJ et al. (2003) Association of TNF-alpha promoter polymorphisms with the clearance of hepatitis B virus infection. |
83. |
Steed PM et al. (2003) Inactivation of TNF signaling by rationally designed dominant-negative TNF variants. |
84. |
Leonardi CL et al. (2003) Etanercept as monotherapy in patients with psoriasis. |
85. |
Diwan A et al. (2004) Targeted overexpression of noncleavable and secreted forms of tumor necrosis factor provokes disparate cardiac phenotypes. |
86. |
Rainero I et al. (2004) Association between the tumor necrosis factor-alpha -308 G/A gene polymorphism and migraine. |
87. |
Bouwmeester T et al. (2004) A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. |
88. |
Boyman O et al. (2004) Spontaneous development of psoriasis in a new animal model shows an essential role for resident T cells and tumor necrosis factor-alpha. |
89. |
Allcock RJ et al. (2004) High-Density SNP genotyping defines 17 distinct haplotypes of the TNF block in the Caucasian population: implications for haplotype tagging. |
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Funayama T et al. (2004) Variants in optineurin gene and their association with tumor necrosis factor-alpha polymorphisms in Japanese patients with glaucoma. |
91. |
Kamata H et al. (2005) Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases. |
92. |
Vielhauer V et al. (2005) Renal cell-expressed TNF receptor 2, not receptor 1, is essential for the development of glomerulonephritis. |
93. |
Balosso S et al. (2005) Tumor necrosis factor-alpha inhibits seizures in mice via p75 receptors. |
94. |
Kim JY et al. (2005) Identification of regulatory polymorphisms in the TNF-TNF receptor superfamily. |
95. |
Laws SM et al. (2005) TNF polymorphisms in Alzheimer disease and functional implications on CSF beta-amyloid levels. |
96. |
Stein CM et al. (2005) Evidence for a major gene influence on tumor necrosis factor-alpha expression in tuberculosis: path and segregation analysis. |
97. |
Murray RZ et al. (2005) A role for the phagosome in cytokine secretion. |
98. |
Stellwagen D et al. (2006) Synaptic scaling mediated by glial TNF-alpha. |
100. |
Ramos EM et al. (2006) Tumor necrosis factor alpha and interleukin 10 promoter region polymorphisms and risk of late-onset Alzheimer disease. |
101. |
Hase H et al. (2006) TNFalpha mediates the skeletal effects of thyroid-stimulating hormone. |
102. |
Kawane K et al. (2006) Chronic polyarthritis caused by mammalian DNA that escapes from degradation in macrophages. |
103. |
Nadkarni S et al. (2007) Anti-TNF-alpha therapy induces a distinct regulatory T cell population in patients with rheumatoid arthritis via TGF-beta. |
104. |
Soller JT et al. (2007) Comparison of the human and canine cytokines IL-1(alpha/beta) and TNF-alpha to orthologous other mammalians. |
105. |
Lieu ZZ et al. (2008) A trans-Golgi network golgin is required for the regulated secretion of TNF in activated macrophages in vivo. |
106. |
Li X et al. (2008) A tumor necrosis factor-alpha-mediated pathway promoting autosomal dominant polycystic kidney disease. |
107. |
Guo R et al. (2008) Ubiquitin ligase Smurf1 mediates tumor necrosis factor-induced systemic bone loss by promoting proteasomal degradation of bone morphogenetic signaling proteins. |
108. |
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Huang MT et al. (2010) Deletion of ripA alleviates suppression of the inflammasome and MAPK by Francisella tularensis. |
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Günther C et al. (2011) Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis. |
112. |
Li Z et al. (2014) The long noncoding RNA THRIL regulates TNFα expression through its interaction with hnRNPL. |
113. |
OMIM.ORG article Omim 191160 |
114. |
Wikipedia article Wikipedia EN (Vascular_dementia) |