Preeclampsia is a disease of pregnancy that occurs after the 20th week of gestation. It is characterized by hypertension and proteinuria and it can develop into a life threatening eclampsia. The cause sometimes can be found in hereditary factors and complement dysregulation.
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None (2003) The genetics of pre-eclampsia: a feto-placental or maternal problem? |
4. |
Page NM et al. (2000) Excessive placental secretion of neurokinin B during the third trimester causes pre-eclampsia. |
5. |
Brown MA et al. (2000) The detection, investigation and management of hypertension in pregnancy: full consensus statement. |
6. |
Moses EK et al. (2000) A genome scan in families from Australia and New Zealand confirms the presence of a maternal susceptibility locus for pre-eclampsia, on chromosome 2. |
7. |
Roberts JM et al. (2001) Pathogenesis and genetics of pre-eclampsia. |
8. |
Esplin MS et al. (2001) Paternal and maternal components of the predisposition to preeclampsia. |
9. |
Zusterzeel PL et al. (2001) A polymorphism in the gene for microsomal epoxide hydrolase is associated with pre-eclampsia. |
10. |
Lachmeijer AM et al. (2001) A genome-wide scan for preeclampsia in the Netherlands. |
11. |
Zusterzeel PL et al. (2002) Paternal contribution to the risk for pre-eclampsia. |
12. |
Laasanen J et al. (2002) Two exonic single nucleotide polymorphisms in the microsomal epoxide hydrolase gene are jointly associated with preeclampsia. |
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Maynard SE et al. (2003) Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia. |
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Wallukat G et al. (1999) Patients with preeclampsia develop agonistic autoantibodies against the angiotensin AT1 receptor. |
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Faisel F et al. (2004) Susceptibility to pre-eclampsia in Finnish women is associated with R485K polymorphism in the factor V gene, not with Leiden mutation. |
16. |
Levine RJ et al. (2004) Circulating angiogenic factors and the risk of preeclampsia. |
17. |
Cnattingius S et al. (2004) Maternal and fetal genetic factors account for most of familial aggregation of preeclampsia: a population-based Swedish cohort study. |
18. |
None (2005) Disentangling fetal and maternal susceptibility for pre-eclampsia: a British multicenter candidate-gene study. |
19. |
Uz E et al. (2007) Extremely skewed X-chromosome inactivation is increased in pre-eclampsia. |
20. |
Kanasaki K et al. (2008) Deficiency in catechol-O-methyltransferase and 2-methoxyoestradiol is associated with pre-eclampsia. |
21. |
Berends AL et al. (2008) Familial aggregation of preeclampsia and intrauterine growth restriction in a genetically isolated population in The Netherlands. |
22. |
Zhou CC et al. (2008) Angiotensin receptor agonistic autoantibodies induce pre-eclampsia in pregnant mice. |
23. |
Payne B et al. (2011) Assessment, surveillance and prognosis in pre-eclampsia. |
24. |
Uzan J et al. (2011) Pre-eclampsia: pathophysiology, diagnosis, and management. |
25. |
van Dijk M et al. (2012) HELLP babies link a novel lincRNA to the trophoblast cell cycle. |
26. |
Oudejans CB et al. (2015) Susceptibility allele-specific loss of miR-1324-mediated silencing of the INO80B chromatin-assembly complex gene in pre-eclampsia. |
27. |
Arngrímsson R et al. (1999) A genome-wide scan reveals a maternal susceptibility locus for pre-eclampsia on chromosome 2p13. |
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Hillermann R et al. (2005) The Glu298Asp variant of the endothelial nitric oxide synthase gene is associated with an increased risk for abruptio placentae in pre-eclampsia. |
29. |
Hiby SE et al. (2004) Combinations of maternal KIR and fetal HLA-C genes influence the risk of preeclampsia and reproductive success. |
30. |
Reidy KJ et al. (2018) Fetal-Not Maternal-APOL1 Genotype Associated with Risk for Preeclampsia in Those with African Ancestry. |
31. |
Dries DL et al. (2005) Corin gene minor allele defined by 2 missense mutations is common in blacks and associated with high blood pressure and hypertension. |
32. |
Wang W et al. (2008) Corin variant associated with hypertension and cardiac hypertrophy exhibits impaired zymogen activation and natriuretic peptide processing activity. |
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Dong N et al. (2013) Corin mutation R539C from hypertensive patients impairs zymogen activation and generates an inactive alternative ectodomain fragment. |
34. |
Pan J et al. (2002) Genomic structures of the human and murine corin genes and functional GATA elements in their promoters. |
35. |
Knappe S et al. (2003) Functional analysis of the transmembrane domain and activation cleavage of human corin: design and characterization of a soluble corin. |
36. |
Guipponi M et al. (2008) An integrated genetic and functional analysis of the role of type II transmembrane serine proteases (TMPRSSs) in hearing loss. |
37. |
Cui Y et al. (2012) Role of corin in trophoblast invasion and uterine spiral artery remodelling in pregnancy. |
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Dong N et al. (2014) Corin mutations K317E and S472G from preeclamptic patients alter zymogen activation and cell surface targeting. [Corrected]. |
39. |
Laivuori H et al. (2003) Susceptibility loci for preeclampsia on chromosomes 2p25 and 9p13 in Finnish families. |
40. |
Chesley LC et al. (1968) The familial factor in toxemia of pregnancy. |
41. |
None (1980) Genetic control of pre-eclampsia. |
42. |
Fisher KA et al. (1981) Hypertension in pregnancy: clinical-pathological correlations and remote prognosis. |
43. |
Van Meter TD et al. (1993) Concerns about the genetics of pre-eclampsia. |
44. |
Brenner B et al. (1996) HELLP syndrome associated with factor V R506Q mutation. |
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Harrison GA et al. (1997) A genomewide linkage study of preeclampsia/eclampsia reveals evidence for a candidate region on 4q. |
46. |
Sohda S et al. (1997) Methylenetetrahydrofolate reductase polymorphism and pre-eclampsia. |
47. |
Arngrímsson R et al. (1997) Evidence for a familial pregnancy-induced hypertension locus in the eNOS-gene region. |
48. |
Lindqvist PG et al. (1998) Factor V Q506 mutation (activated protein C resistance) associated with reduced intrapartum blood loss--a possible evolutionary selection mechanism. |
49. |
Kupferminc MJ et al. (1999) Increased frequency of genetic thrombophilia in women with complications of pregnancy. |
50. |
Thornton JG et al. (1999) Twin mothers, pregnancy hypertension and pre-eclampsia. |
51. |
Zusterzeel PL et al. (1999) Glutathione S-transferase isoenzymes in decidua and placenta of preeclamptic pregnancies. |
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Orphanet article Orphanet ID 275555 |
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Wikipedia article Wikipedia EN (Pre-eclampsia) |