Laboratory for Molecular Diagnostics
Center for Nephrology and Metabolic Disorders
Type 1 of genetic susceptibility to systemic lupus erythematosus is caused by mutations of the TLR5 gene.
| 1. |
Moser KL et al. (1998) Genome scan of human systemic lupus erythematosus: evidence for linkage on chromosome 1q in African-American pedigrees. 
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| 2. |
Hawn TR et al. (2005) A stop codon polymorphism of Toll-like receptor 5 is associated with resistance to systemic lupus erythematosus.
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| 3. |
None (1997) Susceptibility loci for lupus: a guiding light from murine models?
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| 4. |
Tsao BP et al. (1997) Evidence for linkage of a candidate chromosome 1 region to human systemic lupus erythematosus.
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| 5. |
Mohan C et al. (1998) Genetic dissection of SLE pathogenesis. Sle1 on murine chromosome 1 leads to a selective loss of tolerance to H2A/H2B/DNA subnucleosomes.
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| 6. |
Morel L et al. (2001) The major murine systemic lupus erythematosus susceptibility locus, Sle1, is a cluster of functionally related genes.
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| 7. |
Kumar KR et al. (2006) Regulation of B cell tolerance by the lupus susceptibility gene Ly108.
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